Deregulation of VEGFR-2 and PDGFR Expression and Microvascular Density in a Triple-Negative Model of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis

Canine mammary tumors (CMT) represent the most common cancer in noncastrated female dogs.Interestingly, triple-negative tumors are the most common molecular subtype in female dogs.In this study, we proposed to evaluate the expression of vascular endothelial growth factor receptor 2 (VEGFR-2), Platelet-derived growth factor receptor (PDGFR), and mic

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Anorexia nervosa depends on adrenal sympathetic hyperactivity: opposite neuroautonomic profile of hyperinsulinism syndrome

Fuad Lechin1,2, Bertha van der Dijs1,2, Betty Pardey-Maldonado1, Jairo E Rivera1, Scarlet Baez1, Marcel E Lechin31Department of Pathophysiology, Sections of Neuroendocrinology, Neuropharmacology, and Neurochemistry, Instituto de Medicina Experimental, Faculty of Medicine, Universidad Central de Venezuela, Caracas; 2Instituto de Vias Digestivas Cara

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Determinants of Credit Ratings and Comparison of the Rating Prediction Performances of Machine Learning Algorithms

In the literature, new machine learning algorithms are dynamically produced in the field of artificial intelligence engineering Queen Bed and the algorithms are constantly updated with new parameter estimations.The performance of existing algorithms in various business areas is still an important topic of discussion.Also, machine learning algorithm

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Development and Molecular Cytogenetic Identification of a Novel Wheat-Leymus mollis Lm#7Ns (7D) Disomic Substitution Line with Stripe Rust Resistance.

Leymus mollis (2n = Ultrasonic 4x = 28, NsNsXmXm) possesses novel and important genes for resistance against multi-fungal diseases.The development of new wheat-L.mollis introgression lines is of great significance for wheat disease resistance breeding.M11003-3-1-15-8, a novel disomic substitution line of common wheat cv.7182 -L.mollis, developed an

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Improved antioxidant activities of spice require enrichment of distinct yet closely-related metabolic pathways

Improved biosynthesis of commercially and pharmacologically relevant phytometabolites through genetic and metabolic engineering is a lucrative Ovulation Test strategy for crop improvement.However, identifying appropriate biosynthetic pathways pertaining to specific bioactivities has been challenging since the major metabolic pathways remain closely

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